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Buprenorphine Update: Practical Applications & State of the Art Innovations in OBOT

  • Overview
  • Register
  • Faculty
  • Tests / Videos


Overview

Once registered, click on the Tests Tab, then Launch Video.  Note: Viewing of the videos can be completed in one sitting or you may stop and resume at a later time/date. Please make a note where you left off as you will need to advance to that point upon return.  The entire video must be watched in order to claim credit.

You do not have to complete all of the modules at one time. You can complete one, then return to watch other modules at another time. You must watch the module video in its entirety and complete the post-test (attestation) to receive credit.  Once you've viewed all of the modules, you will then need to click on the Tests tab again to complete the post-test (attestation), evaluation and credit claim.

Release Date: July 3, 2024
Expiration Date: July 2, 2027   
                     

Activity Description
Primary care clinicians, mental health and addiction treatment providers who prescribe buprenorphine are faced with the unique clinical challenge of providing daily doses of an opioid to patients with addictive disease. 1. There are challenging clinical issues involved: stabilization v. maintenance doses; treating opiate addicted patients who have concomitant chronic intractable pain; treating opiate addicted patients with co-morbid depressive or anxiety disorders or sleep disturbances; and management of opiate medication side-effects are just a few examples. 2. There are unique ethical issues involved: patient safety v. minimization of disruption to patient daily life and the obligation to the individual patient v. the obligation to the community well-being. 3. There are unique Patient-Doctor and Patient-Treatment Program issues: staff splitting by patients; appropriately supervising toxicology testing while maintaining dignity; patient confidentiality concerns v. the need to have data from other providers regarding patient stability; and issues about dose adjustment, level of supervision and documentation. 4. There are rapidly changing expectations and concerns from regulatory agencies that must be understood and integrated into an evolving standard of care, and documented during increasingly frequent site visits and chart audits. It is for these reasons that faculty from the CWRU School of Medicine Addiction Psychiatry and Addiction Medicine Fellowship Programs has developed this special buprenorphine update.

Course Agenda
Buprenorphine: From the Basics to the Finer Points (1.25 Hour Credit)
Theodore Parran, MD

Buprenorphine Legal and Documentation Update: Federal & State Regulations and the EMR (.50 Hour Credit)
Theodore Parran, MD

Buprenorphine: Harm Reduction v. Adjunct to Sobriety (.50 Hour Credit)
Theodore Parran, MD

Buprenorphine Delivery Systems (.50 Hour Credit)
William Goldman, DO

Emerging Pharmacology of Buprenorphine (.50 Hour Credit)
William Goldman, DO

Getting Started With Buprenorphine Prescribing (.75 Hour Credit)
Theodore Parran, MD

Toxicology Testing when Prescribing Buprenorphine (.50 Hour Credit)
Theodore Parran, MD

Difficult Conversations During OBOT (.50 Hour Credit)
Theodore Parran, MD

Minimizing Diversion While Prescribing Buprenorphine (.50 Hour Credit)
Theodore Parran, MD

“Knowing How To Land” Stopping Buprenorphine RX (.50 Hour Credit)
Theodore Parran, MD

Diagnosis and Management of Anxiety in the OBOT Patient (.75 Hour Credit)
Theodore Parran, MD

Buprenorphine, Chronic Pain and the Patient with Opioid Use Disorder (1.00 Hour Credit)
Theodore Parran, MD

Prescribing Buprenorphine: Summary (.25 Hour Credit)
Theodore Parran, MD

Planning Committee
Course Director
Theodore V. Parran, Jr., MD, FACP
Carter and Isabel Wong Professor of Medical Education
Case Western Reserve University School of Medicine
Dr. Parran, planner for this educational event, has no relevant financial relationship(s) with ineligible companies to disclose.

Amy Ross Pisman
Director
Continuing Medical Education Program
Case Western Reserve University School of Medicine
Ms. Pisman, planner for this educational event, has no relevant financial relationship(s) with ineligible companies to disclose

Faculty
Course Director
Theodore V. Parran, Jr., MD, FACP
Carter and Isabel Wong Professor of Medical Education
Case Western Reserve University School of Medicine
Dr. Parran, faculty for this educational event, has no relevant financial relationship(s) with ineligible companies to disclose.

William Goldman, DO, Diplomate ABPM in Addiction Medicine, FABP
Medical Director, Silver Maple Recovery
Medical Director, Prosperity Haven
Addiction Medicine Provider, Ravenwood Health
Staff Physician, Glenbeigh Hospital
Dr. Goldman, faculty for this educational event, has no relevant financial relationship(s) with ineligible companies to disclose.


Date & Location
Wednesday, July 3, 2024, 8:00 AM - Friday, July 2, 2027, 4:45 PM, Other

Target Audience
Specialties - General Practice, Internal Medicine, Psychiatry

Objectives
After attending this course, participants will be able to:

  1. Describe the pharmacologic profiles of buprenorphine, other opioids, benzodiazepines, THC and psychostimulants with regards to their interaction with the addiction prone brain
  2. Identify approaches to effectively address anxiety / depression / chronic pain / insomnia in the context of OBOT
  3. Employ techniques relating to minimizing the diversion of buprenorphine including use of different delivery systems
  4. Discuss risk management, office documentation and best practice guidelines for buprenorphine prescribing as well as evolving and emerging State and Federal requirements
  5. Practice difficult conversations when maintaining boundaries and clinical expectations in the OBOT clinic
  6. Compare and contrast “harm reduction” with “adjunct to sobriety” OBOT treatment approaches

Registration

$150

Resident/Fellow: Reduced $75 with Promo Code (Send letter from Program Director documenting residency status to [email protected] and a code will be emailed to you)


Accreditation

Case Western Reserve University School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Case Western Reserve University School of Medicine designates this enduring material for a maximum of 8.0 AMA PRA Category 1™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.


Credits
AMA PRA Category 1 Credits™ (8.00 hours), Non-Physician Attendance (8.00 hours)

Mitigation of Relevant Financial Relationships


CWRU School of Medicine adheres to the ACCME’s Standards for Integrity and Independence in Accredited Continuing Education. Any individuals in a position to control the content of a CE activity, including faculty, planners, reviewers or others are required to disclose all relevant financial relationships with ineligible entities (commercial interests). All relevant conflicts of interest have been mitigated prior to the commencement of the activity.

William Goldman, DO
Medical Director, Silver Maple Recovery and Prosperity Haven
Addiction Medicine Provider, Ravenwood Health
Theodore Parran, MD
Carter and Isabel Wong Professor of Medical Education
Case Western Reserve University School of Medicine

Wednesday, July 3, 2024
Buprenorphine: From the Basics to the Finer Points
8:00AM - 8:10AM
Theodore Parran, MD
Buprenorphine Legal and Documentation Update: Federal & State Regulations and the EMR
8:10AM - 8:20AM
Theodore Parran, MD
Buprenorphine: Harm Reduction v. Adjunct to Sobriety
8:20AM - 8:30AM
Theodore Parran, MD
Buprenorphine Delivery Systems
8:30AM - 8:40AM
William Goldman, DO
Emerging Pharmacology of Buprenorphine
8:40AM - 8:50AM
William Goldman, DO
Getting Started With Buprenorphine Prescribing
8:50AM - 9:00AM
Theodore Parran, MD
Toxicology Testing when Prescribing Buprenorphine
9:00AM - 9:10AM
Theodore Parran, MD
Difficult Conversations During OBOT
9:10AM - 9:20AM
Theodore Parran, MD
Minimizing Diversion While Prescribing Buprenorphine
9:20AM - 9:30AM
Theodore Parran, MD
“Knowing How To Land” Stopping Buprenorphine RX
9:30AM - 9:40AM
Theodore Parran, MD
Diagnosis and Management of Anxiety in the OBOT Patient
9:40AM - 9:50AM
Theodore Parran, MD
Buprenorphine, Chronic Pain and the Patient with Opioid Use Disorder
9:50AM - 10:00AM
Theodore Parran, MD
Prescribing Buprenorphine: Summary
10:00AM - 10:10AM
Theodore Parran, MD
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Buprenorphine: From the Basics to the Finer Points

Presented by:  Theodore Parran, MD
Note: Viewing of this video can be completed in one sitting or you may stop and resume at a later time/date. Please make a note where you left off as you will need to advance to that point upon return. You must watch the video in its entirety and complete the post-test (attestation) before the next video becomes available.

Downloadable Material:  https://bit.ly/BupResources

Resources:
https://addiction.surgeongeneral.gov/surgeon-generals-report.pdf
http://www.cdc.gov/drugoverdose/data/overdose.html
https://www.cdc.gov/vitalsigns/opioids/index.html
 https://www.cdc.gov/opioids/basics/epidemic.html
Parran T. Prescription Drug Abuse: a question of balance. Medical Clinics of North America. 1997. 81(4), 967-978.
Opioid Prescribing After Nonfatal Overdose and Association With Repeated Overdose A Cohort Study. Marc R. Larochelle, MD, MPH; Jane M. Liebschutz, MD, MPH; Fang Zhang, PhD; Dennis Ross-Degnan, ScD; and J. Frank Wharam, MB, BCh, BAO, MPH Ann Intern Med. 2016;164:1-9. doi:10.7326/M15-0038
Parran TV, Jasinski DR. Intravenous methylphenidate abuse: prototype for prescription drug abuse. Archives of internal medicine. 1991 Apr 1;151(4):781-3.
Longo LP, Parran Jr T, Johnson B, Kinsey W. Addiction: part II. Identification and management of the drug-seeking patient. American family physician. 2000 Apr;61(8):2401-8.
Chapter 6 Pain Management Considerations, Parran T. In “The Pharmacist's Guide to Opioid Use Disorders” Merrill Norton eds 2018
Ries R, Fiellin D, Saitz R. The ASAM Principles of Addiction Medicine. Buprenorphine and MOUD. 2024. Lippincott Williams & Wilkins.
Campbell N, Lovell A. The history of the development of buprenorphine as an addiction therapeutic. Ann. N.Y. Acad. Sci. 2012;1248:124–139
Classics in Chemical Neuroscience: Buprenorphine Jillian L. Kyzer and Cody J. Wenthur ACS Chemical Neuroscience 2020 11 (10), 1385-1399

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Buprenorphine Legal and Documentation Update: Federal & State Regulations and the EMR

Presented by:  Theodore Parran, MD

Note: Viewing of this video can be completed in one sitting or you may stop and resume at a later time/date. Please make a note where you left off as you will need to advance to that point upon return. You must watch the video in its entirety and complete the post-test (attestation) before the next video becomes available.

Resources:
https://www.deadiversion.usdoj.gov/pubs/docs/MATE_Training_Letter_Final.pdf
https://www.hsdl.org/c/2016-national-drug-threat-assessment/
Campbell N, Lovell A. The history of the development of buprenorphine as an addiction therapeutic. Ann. N.Y. Acad. Sci. 2012;1248:124–139
20.Stahl S. Essential Psychopharmacology: Neuroscientific Basis and Practical Applications, 2nd Edition. 2000. Cambridge Univ. Press. 
 Classics in Chemical Neuroscience: Buprenorphine Jillian L. Kyzer and Cody J. Wenthur ACS Chemical Neuroscience 2020 11 (10), 1385-1399 
Parran T. Prescription Drug Abuse: a question of balance. Medical Clinics of North America. 1997. 81(4), 967-978. Opioid Prescribing After Nonfatal Overdose and Association With Repeated Overdose A Cohort Study. Marc R. Larochelle, MD, MPH; Jane M. Liebschutz, MD, MPH; Fang Zhang, PhD; Dennis Ross-Degnan, ScD; and J. Frank Wharam, MB, BCh, BAO, MPH Ann Intern Med. 2016;164:1-9. doi:10.7
Opioid Prescribing After Nonfatal Overdose and Association With Repeated Overdose A Cohort Study. Marc R. Larochelle, MD, MPH; Jane M. Liebschutz, MD, MPH; Fang Zhang, PhD; Dennis Ross-Degnan, ScD; and J. Frank Wharam, MB, BCh, BAO, MPH Ann Intern Med. 2016;164:1-9. doi:10.7326/M15-0038  
Parran TV, Jasinski DR. Intravenous methylphenidate abuse: prototype for prescription drug abuse. Archives of internal medicine. 1991 Apr 1;151(4):781-3.

Ries R, Fiellin D, Saitz R. The ASAM Principles of Addiction Medicine. Buprenorphine and MOUD. 2024. Lippincott Williams & Wilkins. 

Purchase
Buprenorphine: Harm Reduction v. Adjunct to Sobriety

Presented by:  Theodore Parran, MD

Note: Viewing of this video can be completed in one sitting or you may stop and resume at a later time/date. Please make a note where you left off as you will need to advance to that point upon return. You must watch the video in its entirety and complete the post-test (attestation) before the next video becomes available.

Resources:  
https://www.cdc.gov/media/releases/2023/p0329-covid-opioids.html  
Campbell N, Lovell A. The history of the development of buprenorphine as an addiction therapeutic. Ann. N.Y. Acad. Sci. 2012;1248:124–139  
Classics in Chemical Neuroscience: Buprenorphine Jillian L. Kyzer and Cody J. Wenthur ACS Chemical Neuroscience 2020 11 (10), 1385-1399 

Ries R, Fiellin D, Saitz R. The ASAM Principles of Addiction Medicine. Buprenorphine and MOUD. 2024. Lippincott Williams & Wilkins.  

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Buprenorphine Delivery Systems
Presented by:  William Goldman, DO

Note: Viewing of this video can be completed in one sitting or you may stop and resume at a later time/date. Please make a note where you left off as you will need to advance to that point upon return. You must watch the video in its entirety and complete the post-test (attestation) before the next video becomes available.

Resources:

  • Campbell N, Lovell A. The history of the development of buprenorphine as an addiction therapeutic. Ann. N.Y. Acad. Sci. 2012;1248:124–139
  • Kuhlman J, et al. Human Pharmacokinetics of Intravenous, Sublingual and Buccal Buprenorphine. J Anal Tox. 1996;20:369-378
  • Compton P, Ling W, et al. Pharmacokinetics of Buprenorphine: A Comparison of Sublingual Tablet Versus Liquid after Chronic Dosing. J Addict Med. 2007;1:88–95
  • Elkader A, Sproule B. Buprenorphine: Clinical Pharmacokinetics in the Treatment of Opioid Dependence. Clin Pharmacokinet. 2005;44(7):661-680
  • Peng H, Kehner G, et al. Comparison of Pharmacological Activities of Buprenorphine and Norbuprenorphine: Norbuprenorphine Is a Potent Opioid Agonist. J Pharm Exp Ther. 2001;297(2): 688-695
  • Rosenthal R, et al. Effect of Buprenorphine Implants on Illicit Opioid Use Among Abstinent Adults With Opioid Dependence Treate22.
  •  Classics in Chemical Neuroscience: Buprenorphine Jillian L. Kyzer and Cody J. Wenthur ACS Chemical Neuroscience 2020 11 (10), 1385-1399 d With Sublingual Buprenorphine - A Randomized Clinical Trial. JAMA. 2016;316(3):282-290
  • Greenwald M, et al. Buprenorphine maintenance and mu-opioid receptor availability in the treatment of opioid use disorder: Implications for clinical use and policy. Drug Alcohol Depend. 2014;144:1-11 
  • Ries R, Fiellin D, Saitz R. The ASAM Principles of Addiction Medicine. Buprenorphine and MOUD. 2024. Lippincott Williams & Wilkins. 
  • https://www.sublocade.com/
Purchase
Emerging Pharmacology of Buprenorphine

Presented by:  William Goldman, DO

Note: Viewing of this video can be completed in one sitting or you may stop and resume at a later time/date. Please make a note where you left off as you will need to advance to that point upon return. You must watch the video in its entirety and complete the post-test (attestation) before the next video becomes available.

Resources:

  • Ries R, Fiellin D, Saitz R. The ASAM Principles of Addiction Medicine. 2014. Lippincott Williams & Wilkins.
  • Stahl S. Essential Psychopharmacology: Neuroscientific Basis and Practical Applications, 2nd Edition. 2000. Cambridge Univ. Press.
  • Campbell N, Lovell A. The history of the development of buprenorphine as an addiction therapeutic. Ann. N.Y. Acad. Sci. 2012;1248:124–139
  • Greenwald M, et al. Buprenorphine maintenance and mu-opioid receptor availability in the treatment of opioid use disorder: Implications for clinical use and policy. Drug Alcohol Depend. 2014;144:1-11
  • Peng H, Kehner G, et al. Comparison of Pharmacological Activities of Buprenorphine and Norbuprenorphine: Norbuprenorphine Is a Potent Opioid Agonist. J Pharm Exp Ther. 2001;297(2): 688-695
  • Classics in Chemical Neuroscience: Buprenorphine Jillian L. Kyzer and Cody J. Wenthur ACS Chemical Neuroscience 2020 11 (10), 1385-1399
Purchase
Getting Started With Buprenorphine Prescribing

Presented by:  Theodore Parran, MD

Note: Viewing of this video can be completed in one sitting or you may stop and resume at a later time/date. Please make a note where you left off as you will need to advance to that point upon return. You must watch the video in its entirety and complete the post-test (attestation) before the next video becomes available.


Resources:
  • Bickel WK et al.  Psychopharmacology 146:111-118, 1999.
  • Johnson RE  et al. Drug Alcohol Depend.  40:27-35, 1995.
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Toxicology Testing when Prescribing Buprenorphine

Presented by:  Theodore Parran, MD


Note: Viewing of this video can be completed in one sitting or you may stop and resume at a later time/date. Please make a note where you left off as you will need to advance to that point upon return. You must watch the video in its entirety and complete the post-test (attestation) before the next video becomes available.

Resources: 
 See downloadable materials https://bit.ly/BupResources

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Difficult Conversations During OBOT

Presented by:  Theodore Parran, MD

Note: Viewing of this video can be completed in one sitting or you may stop and resume at a later time/date. Please make a note where you left off as you will need to advance to that point upon return. You must watch the video in its entirety and complete the post-test (attestation) before the next video becomes available.

Resources:

  • Parran TV, Jasinski DR. Intravenous methylphenidate abuse: prototype for prescription drug abuse. Archives of internal medicine. 1991 Apr 1;151(4):781-3.
  • Ries R, Fiellin D, Saitz R. The ASAM Principles of Addiction Medicine. Buprenorphine and MOUD. 2024. Lippincott Williams & Wilkins. 
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Minimizing Diversion While Prescribing Buprenorphine

Presented by:  Theodore Parran, MD

Note: Viewing of this video can be completed in one sitting or you may stop and resume at a later time/date. Please make a note where you left off as you will need to advance to that point upon return. You must watch the video in its entirety and complete the post-test (attestation) before the next video becomes available.

Resources:

  • Parran T. Prescription Drug Abuse: a question of balance. Medical Clinics of North America. 1997. 81(4), 967-978. 
  • Dowell D, Kunins HV, Farley TA. Opioid analgesics—risky drugs, not risky patients. Jama. 2013 Jun 5;309(21):2219-20.
  • Opioid Prescribing After Nonfatal Overdose and Association With Repeated Overdose A Cohort Study. Marc R. Larochelle, MD, MPH; Jane M. Liebschutz, MD, MPH; Fang Zhang, PhD; Dennis Ross-Degnan, ScD; and J. Frank Wharam, MB, BCh, BAO, MPH Ann Intern Med. 2016;164:1-9. doi:10.7326/M15-0038 
  • Longo LP, Parran Jr T, Johnson B, Kinsey W. Addiction: part II. Identification and management of the drug-seeking patient. American family physician. 2000 Apr;61(8):2401-8. 
  • https://med.ohio.gov/Portals/0/Resources/Prescriber%20Resources/Issuing%20a%20Valid%20Prescription%20-%20What%20Every%20Prescriber%20Needs%20to%20Know.pdf 
  • Peng H, Kehner G, et al. Comparison of Pharmacological Activities of Buprenorphine and Norbuprenorphine: Norbuprenorphine Is a Potent Opioid Agonist. J Pharm Exp Ther. 2001;297(2): 688-695 
  • Rosenthal R, et al. Effect of Buprenorphine Implants on Illicit Opioid Use Among Abstinent Adults With Opioid Dependence Treated With Sublingual Buprenorphine - A Randomized Clinical Trial. JAMA. 2016;316(3):282-290
  • https://www.sublocade.com/ 
  • Classics in Chemical Neuroscience: Buprenorphine Jillian L. Kyzer and Cody J. Wenthur ACS Chemical Neuroscience 2020 11 (10), 1385-1399 
  • Ries R, Fiellin D, Saitz R. The ASAM Principles of Addiction Medicine. Buprenorphine and MOUD. 2024. Lippincott Williams & Wilkins. 
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“Knowing How To Land” Stopping Buprenorphine RX

Presented by:  Theodore Parran, MD

Note: Viewing of this video can be completed in one sitting or you may stop and resume at a later time/date. Please make a note where you left off as you will need to advance to that point upon return. You must watch the video in its entirety and complete the post-test (attestation) before the next video becomes available.

Resources:

  • Parran T. Prescription Drug Abuse: a question of balance. Medical Clinics of North America. 1997. 81(4), 967-978. 
  • Opioid Prescribing After Nonfatal Overdose and Association With Repeated Overdose A Cohort Study. Marc R. Larochelle, MD, MPH; Jane M. Liebschutz, MD, MPH; Fang Zhang, PhD; Dennis Ross-Degnan, ScD; and J. Frank Wharam, MB, BCh, BAO, MPH Ann Intern Med. 2016;164:1-9. doi:10.7326/M15-0038 
  • Parran TV, Jasinski DR. Intravenous methylphenidate abuse: prototype for prescription drug abuse. Archives of internal medicine. 1991 Apr 1;151(4):781-3.
  • Chapter 6 Pain Management Considerations, Parran T. In “The Pharmacist's Guide to Opioid Use Disorders” Merrill Norton eds 2018 
  • Stahl S. Essential Psychopharmacology: Neuroscientific Basis and Practical Applications, 2nd Edition. 2000. Cambridge Univ. Press. 
  • Ries R, Fiellin D, Saitz R. The ASAM Principles of Addiction Medicine. Buprenorphine and MOUD. 2024. Lippincott Williams & Wilkins. 
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Diagnosis and Management of Anxiety in the OBOT Patient

Presented by:  Theodore Parran, MD

Note: Viewing of this video can be completed in one sitting or you may stop and resume at a later time/date. Please make a note where you left off as you will need to advance to that point upon return. You must watch the video in its entirety and complete the post-test (attestation) before the next video becomes available.

Resources:

  • REFERENCE: Center for Behavioral Health Statistics and Quality.(2015). Behavioral health trends in the United States: Results from the 2014 National Survey on Drug Use and Health (HHS Publication No. SMA 15-4927, NSDUH Series H-50).
  • REFERENCE: Substance Abuse and Mental Health Services Administration, Center for Behavioral Health Statistics and Quality. (February 5, 2013). The NSDUH Report: Smoking and Mental Illness. Rockville, MD.
  • Center for Behavioral Health Statistics and Quality.(2015). Behavioral health trends in the United States: Results from the 2014 National Survey on Drug Use and Health (HHS Publication No. SMA 15-4927, NSDUH Series H-50). 
  • ASAM Principles of Addiction Medicine, 5th Edition
    https://www.drugabuse.gov/publications/research-reports/comorbidity-addiction-other-mental-illnesses/letter-director
  • Substance Abuse and Mental Health Services Administration, Center for Behavioral Health Statistics and Quality. (February 5, 2013). The NSDUH Report: Smoking and Mental Illness. Rockville, MD.
  • Casher, Michael I.; Gih, Daniel et al. “Benzodiazepines and Stimulants for Patients with Substance Use Disorder.” Current Psychiatry, May 2011, p58-66.
  • Cook, Lane. “After substance withdrawal, underlying psychiatric symptoms emerge.” Current Psychiatry, Dec 2014, p27-32.
  • Earley PH, Merkin B, Skipper G. The medication guide for safe recovery. Revision 1.7. Published March 2014.
  • McKay M, Davis M, and Fanning P. Thoughts and Feelings, 4th Edition. Oakland: New Harbinger Publications, Inc. 2011.
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Buprenorphine, Chronic Pain and the Patient with Opioid Use Disorder

Presented by:  Theodore Parran, MD

Note: Viewing of this video can be completed in one sitting or you may stop and resume at a later time/date. Please make a note where you left off as you will need to advance to that point upon return. You must watch the video in its entirety and complete the post-test (attestation) before the next video becomes available.

Resources:
  • O'Brien CP. Drug addiction and drug abuse. In: Goodman and Gilman's The pharmacological basis of therapeutics. 9th edition.
  • Heit HA, Gourlay DL. Treatment of Pain in Substance Abuse Disordered Population. Ballantyne JC, Rathmell JP, Fishman SM (eds). Bonica’s Management of Pain. 4th ed. Lippincott Williams & Wilkins. In Press.
  • *Weissman D, Haddox J. Opioid pseodoaddiction-an iatrogenic syndrome. Pain 1989;36:363-6 *Case Report
  • Balantyne JC, Mao J. NEJM 2003, APS 2009 Guidelines 
  • Martell BA et al. Ann Intern Med 2007;  Eisenberg E et al. JAMA. 2005
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Prescribing Buprenorphine: Summary

Presented by:  Theodore Parran, MD

Note: Viewing of this video can be completed in one sitting or you may stop and resume at a later time/date. Please make a note where you left off as you will need to advance to that point upon return. You must watch the video in its entirety and complete the post-test (attestation) before the next video becomes available.

Upon completion of this module, be sure to complete the test AND evaluation/credit claim (available at end of test).  

Resources:
CDC Guideline for Prescribing Opioids for Chronic Pain http://dx.doi.org/10.15585/mmwr.rr6501e1 
Dowell D, Kunins HV, Farley TA. Opioid analgesics—risky drugs, not risky patients. Jama. 2013 Jun 5;309(21):2219-20
Chapter 6 Pain Management Considerations, Parran T. In “The Pharmacist's Guide to Opioid Use Disorders” Merrill Norton eds 2018

Campbell N, Lovell A. The history of the development of buprenorphine as an addiction therapeutic. Ann. N.Y. Acad. Sci. 2012;1248:124–139 
Ries R, Fiellin D, Saitz R. The ASAM Principles of Addiction Medicine. Buprenorphine and MOUD. 2024. Lippincott Williams & Wilkins. 

 

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